con el diagnóstico histopatológico de cordoma de la base del cráneo .. magnética cerebral, corte sagital, secuencia T1, cordoma del clivus. Resección endoscópica de cordoma del clivus. Descripción de un chordoma; clivus; endoscopic resection; malignant tumor. RESUMEN. Download Citation on ResearchGate | On Dec 19, , Ines Gamboa and others published Resección endoscópica de cordoma del clivus. Descripción de un.

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Also, this tumor contained a necrotic materials.

The Journal of Bone and Joint Surgery. The disc protrusion at the L-2 interspace was considered clinically significant in that it explained the presence of pain in the right thigh. This is in sharp distinction to chordomas of the vertebral bodies, which are virtually unresectable.

Support Radiopaedia and see fewer ads. Preoperative MR images presenting the intradural retroclival tumor with growing into right cavernous sinus and Meckel’s cave. Published online Aug As in the case of chordoma of true vertebrae, our patient’s lesion did not deel peripheral amorphous calcification, a common feature of sacral lesions.

Microscopically, chordomas are characterised by physaliphorous cells. In contrast, radiosurgery has the advantage of high dose single-session irradiation and efficacy for small sized tumor mass 7 In four of these families, duplication of the brachyury gene was found to be responsible for causing chordoma.

The patient complained dizziness, but cordlma symptoms, such as ataxia, right facial numbness without paralysis, right hearing disturbance, were much more improved.

Intradural Retroclival Chordoma

Find articles by Sun-Il Lee. However, stereotactic radiosurgery is valuable as an adjuvant or primary treatment for selected patients with chordoma and has potential advantages over standard fractionated irradiation, although the length of follow-up review has been insufficient 7. The differential diagnosis of ecchordosis physaliphora and chordoma based on histological and radiological features is likely to be difficult. Chordomas Chordoma – General Chordomas – general.


The role of radiosurgery in the management of chordoma and chondrosarcoma of the cranial base. In contrast to sacrococcygeal tumours, there is no recognised gender difference.

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The MIB-1 proliferating cell index may be useful in the histological differential diagnosis of chordomas, which are neoplastic tumors, and ecchordoses, which are not true tumor Percutaneous radiofrequency ablation has been trialled as an adjunct therapy 8.

Discussion The interest of this case lies not only in the nature and location of the incidentally discovered tumor but also in its radiological presentation as an asymptomatic lesion at one lumbar level associated with a symptomatic disc extrusion at another lumbar level. Synonyms or Alternate Spellings: Typically the mass projects posteriorly at midline, indenting the pons; this characteristic appearance has been termed the so-called thumb sign.

Intradural Retroclival Chordoma

This dose may carry a high risk of severe radiation injury to the normal brain structures 9. A portion of the tumor with typical features of physaliphorous cells.

Surgical Implications The tumor in our patient lent itself to complete surgical removal.

Our experience suggests that at least some cranial chordomas enhance unpublished data. Under the impression of acoustic schwannoma, the patient underwent operation.

In fact, the imaging findings were atypical for vertebral chordoma and more characteristic of either a neurogenic neoplasm, such as neurilemoma or neurofibroma, an arachnoid cyst, or diverticulum. The MR appearance of our patient’s tumor was dissimilar to that of true vertebral chordomas because of its extraosseous location. They most commonly involve cervical particularly C2followed by lumbar, and then the thoracic spine.


Back pain was ascribed to both the extruded disc and the mass effect of the epidural lesion. MR images, performed 14 months after gammaknife radiosurgery, representing decreased remnant tumor in size. Also, proton-beam irradiation is reported to be efficacious for the treatment of chordomas SpineCentral Nervous SystemMusculoskeletal.

Extraosseous spinal chordoma in: Journal of Neurosurgery Volume 75 Issue 6 Year

Additionally, it represents an example of intraspinal extraosseous chordoma, a lesion not previously described. A purported example with unusual light microscopic features was reported by Maesen, et al. The remainder of the neurological examination was within normal ranges. The only abnormality demonstrated on CT was scalloping of the posterior portion of the vertebral body and enlargement of the neural foramen, both frequently seen in neurogenic tumors.

MR imaging, performed 14months after gamma knife radiosurgery, revealed decreased size of remnant tumor compared with one before gamma knife radiosurgery Fig. This page was last edited on 14 Novemberat Clovus locations included the prepontine region in ten cases, the suprasellar region in two cases and the intrasellar, foramen magnum, tentorium and ponto-cerebellar region in one case, respectively.

In contrast, the intradural type of tumor characteristically has a slower growth pattern, sharply circumscribed margins that allow total excision, and it never metastasizes 611 The prognosis in such cases dwl poor. Yeon Soo ChooM. Chordomas can arise from bone in the skull base and anywhere along the spine.